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On tirzepatide, patients frequently describe an additional layer: reduced food interest between meals, fewer cravings, and less mental preoccupation with food

3.3 UPF and anxiety 3.3.1 Background on known mechanisms of anxiety As of 2021, an estimated 4.4% of the global population experiences an anxiety disorder, making it the most prevalent mental disorder (111)

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3.3 7,8-DHF metabolites in plasma and brain O-methylated metabolites were detected in plasma and brain using the semi-quantitative approach